SCHEMBL915503

SCHEMBL915503

O=[PH](OCc1ccc2ccccc2c1)OCc1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.50
CYP1A2 P05177 2/20 0.48
CYP2A6 P11509 1/20 0.48
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
SLC6A2 P23975 3/20 0.45
SLC6A4 P31645 3/20 0.45
SLC6A3 Q01959 3/20 0.45
HTR2A P28223 2/20 0.45
HTR2C P28335 2/20 0.45
HTR2B P41595 2/20 0.45
HTR7 P34969 1/20 0.45
HTR3A P46098 1/20 0.45
HTR4 Q13639 1/20 0.45
ALOX5 P09917 3/20 0.43
KCNH2 Q12809 2/20 0.43
CNR1 P21554 2/20 0.42
CNR2 P34972 2/20 0.42
TLR4 O00206 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16825144 0.85 RAB9A (0.47) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL7301505 0.79 PLAU (0.47) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL8728877 0.78 CYP1A2 (0.54) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL433146 0.77 CYP1A2 (0.58) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL28936084 0.77 CYP1A2 (0.54) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL29806030 0.74 TSHR (0.52) RAB9ACYP1A2SLC6A2SLC6A3MAOA
SCHEMBL28367677 0.74 RAB9A (0.51) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL2001872 0.74 SLC1A3 (0.50) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL1262275 0.74 CYP1A2 (0.54) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2
SCHEMBL2129850 0.74 CYP1A2 (0.54) RAB9ACYP1A2CYP2A6SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083584-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS Sunshine Lake Pharma Co., Ltd. (CN) 2016-10-26 EP disclosed
WO-2015090232-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS SUNSHINE LAKE PHARMA CO., LTD. (CN) 2015-06-25 WO disclosed
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed