Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10354233 | 0.88 | HTR6 (0.62) | HTR6AKR1B1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL1573955 | 0.73 | TSHR (0.48) | HTR6AKR1B1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL16528 | 0.73 | GAA (0.39) | GAAALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL3377180 | 0.72 | PKM (0.59) | HTR6AKR1B1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL11370935 | 0.72 | HTT (0.49) | GAAHTR6AKR1B1ALDH1A1TDP1 | |
| SCHEMBL5334272 | 0.71 | CA1 (0.42) | GAAALDH1A1KDM4EPKMHTT | |
| SCHEMBL30252450 | 0.71 | GAA (0.38) | GAAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL427846 | 0.71 | GAA (0.38) | GAAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL1156253 | 0.71 | GAA (0.38) | GAAALDH1A1KDM4EPKMHTT | |
| SCHEMBL31338952 | 0.71 | HTR6 (0.50) | HTR6AKR1B1ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497258-B1 | Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0467248-B1 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5338743-A | Pancreatitis | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5204346-A | Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0497258-A2 | Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0467248-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |