Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15610559 | 0.87 | RAB9A (0.65) | RAB9AALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15610145 | 0.84 | RAB9A (0.56) | RAB9AALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9268117 | 0.82 | HPGD (0.62) | ALDH1A1MEN1KMT2ACTSDHTT | |
| SCHEMBL15609584 | 0.81 | RAB9A (0.65) | RAB9AALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL13108487 | 0.81 | CTSD (0.59) | ALDH1A1MEN1KMT2ACTSDHTT | |
| SCHEMBL15610320 | 0.81 | RAB9A (0.53) | RAB9AALDH1A1MEN1KMT2AHTT | |
| SCHEMBL3897907 | 0.81 | CTSD (0.66) | ALDH1A1MEN1KMT2ACTSDHTT | |
| SCHEMBL19246188 | 0.79 | KMT2A (0.75) | ALDH1A1MEN1KMT2ACTSDHTT | |
| SCHEMBL30236290 | 0.79 | KMT2A (0.75) | ALDH1A1MEN1KMT2ACTSDHTT | |
| SCHEMBL2706463 | 0.79 | ALDH1A1 (0.61) | RAB9AALDH1A1MEN1KMT2ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354855-A | Preparation method of cilansetrot sodium | 江苏百奥信康医药科技有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116354855-B | Preparation method of cilansetrot sodium | 江苏百奥信康医药科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116354855-B | Preparation method of cilansetrot sodium | 江苏百奥信康医药科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116354855-A | Preparation method of cilansetrot sodium | 江苏百奥信康医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116354855-A | Preparation method of cilansetrot sodium | 江苏百奥信康医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-5359121-A | N-(o-(p-pivaloyloxybenzenesulfonylamino)benzoyl)glycine benzyl ester; elastase inhibitor; useful for treatment of emphysema, atherosclerosis, rheumatoid arthritis | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0539223-A1 | Glycine derivative monosodium salt tetrahydrate having an inhibitory effect on elastase | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |