Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451176 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TDP1L3MBTL1RAB9AKMT2A | |
| SCHEMBL12569605 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TDP1L3MBTL1RAB9AKMT2A | |
| SCHEMBL2014208 | 0.87 | TSHR (0.60) | ALDH1A1TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2005800 | 0.87 | RAB9A (0.59) | ALDH1A1TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL6276517 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TDP1L3MBTL1RAB9AKMT2A | |
| SCHEMBL7886556 | 0.85 | TDP1 (0.54) | ALDH1A1TDP1L3MBTL1RAB9AKMT2A | |
| SCHEMBL2009221 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1RAB9AKMT2A | |
| SCHEMBL5663592 | 0.85 | L3MBTL1 (0.51) | ALDH1A1TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2704301 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL29172358 | 0.85 | L3MBTL1 (0.62) | ALDH1A1TDP1L3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204490-B | Preparation method of disubstituted 4-chloroquinoline-3-carbonitrile derivative and bosutinib | 新发药业有限公司 | 2021-01-01 | — | — | CN | disclosed |
| EP-2609067-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | Sumitomo Chemical Co., Ltd (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20130150611-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-13 | — | — | US | disclosed |
| WO-2012176930-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012026617-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | WO | disclosed |
| CN-1110484-C | 2-(arylphenyl) amino-imidazoline derivatives | HOFMMANN LA ROCHE AG F (CH) | 2003-06-04 | — | — | CN | disclosed |
| CN-1216762-A | 2-(arylphenyl) amino-imidazoline derivatives | HOFMMANN LA ROCHE AG F (CH) | 1999-05-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150611-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | ADH5, ADH1A, ADH1C | ALDH1A1 33/4885TDP1 4303/4885L3MBTL1 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.