Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298470 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7299287 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7302756 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7365452 | 0.76 | PPARG (0.43) | — | |
| SCHEMBL7298114 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7765079 | 0.72 | TSHR (0.58) | ALDH1A1PKMMAPTLMNAKDM4E | |
| SCHEMBL7302910 | 0.70 | TP53 (0.44) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7302767 | 0.70 | SMN1; SMN2 (0.45) | ALDH1A1PKMMAPTLMNAKDM4E | |
| SCHEMBL3999898 | 0.70 | KDM4E (0.55) | ALDH1A1PKMMAPTLMNAKDM4E | |
| SCHEMBL10469566 | 0.70 | CA12 (0.68) | ALDH1A1PKMMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |