Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397683 | 0.78 | MAOB (0.50) | MAOBMAOARAB9ARXRBKCNH2 | |
| SCHEMBL7300477 | 0.74 | PPARA (0.49) | MAOBMAOARAB9ARXRBKCNH2 | |
| SCHEMBL7300468 | 0.73 | RAB9A (0.44) | MAOBMAOARAB9ARXRBKCNH2 | |
| SCHEMBL7434670 | 0.72 | MAOB (0.48) | MAOBMAOARAB9ARXRBKCNH2 | |
| SCHEMBL2115724 | 0.70 | ALDH1A1 (0.51) | L3MBTL1KDM4EFFAR1MEN1LMNA | |
| SCHEMBL7307184 | 0.70 | MAOB (0.46) | MAOBMAOARAB9AKCNH2PPARD | |
| SCHEMBL22070895 | 0.69 | CYP11B1 (0.42) | L3MBTL1KDM4EPPARDPPARACYP11B1 | |
| SCHEMBL31318415 | 0.69 | ACHE (0.53) | MAOBMAOA | |
| SCHEMBL7312304 | 0.69 | PPARA (0.53) | MAOBMAOARAB9ARXRBKCNH2 | |
| SCHEMBL7302211 | 0.69 | RXRB (0.45) | MAOBMAOARAB9ARXRBPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |