Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304078 | 0.83 | PPARD (0.39) | PPARAPPARDRAB9AFFAR1S1PR1 | |
| SCHEMBL7312304 | 0.83 | PPARA (0.53) | PPARAPPARDRAB9AMAOBMAOA | |
| SCHEMBL7300008 | 0.78 | ITGB3 (0.41) | PPARAPPARDRAB9AFFAR1S1PR1 | |
| SCHEMBL7297140 | 0.77 | MCHR1 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7306501 | 0.77 | MCHR1 (0.52) | RAB9AITGB3ITGA2B | |
| SCHEMBL7303281 | 0.77 | PGR (0.40) | PPARAPPARD | |
| SCHEMBL7302216 | 0.74 | MAOB (0.47) | PPARAPPARDRAB9AMAOBMAOA | |
| SCHEMBL7300393 | 0.73 | AKR1C4 (0.42) | PPARAPPARDFFAR1 | |
| SCHEMBL7299593 | 0.73 | ALDH1A1 (0.40) | PPARAPPARDITGB3ITGA2B | |
| SCHEMBL7307184 | 0.72 | MAOB (0.46) | PPARAPPARDRAB9AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |