Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302300 | 0.77 | PDPK1 (0.62) | PDPK1DAOKDM4EALDH1A1GAA | |
| SCHEMBL31297662 | 0.74 | PDPK1 (0.65) | PDPK1DAOKDM4EALDH1A1GAA | |
| SCHEMBL31549260 | 0.73 | F7 (0.43) | DAOKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL22144475 | 0.73 | PDPK1 (0.62) | PDPK1DAOALDH1A1PARP1CSNK2A2 | |
| SCHEMBL4146436 | 0.70 | DAO (0.61) | DAOKDM4EALDH1A1POLBGAA | |
| SCHEMBL2793777 | 0.69 | CYP3A4 (0.50) | DAOKDM4EALDH1A1GAACSNK2A2 | |
| SCHEMBL7308279 | 0.69 | PARP1 (0.47) | PDPK1DAOKDM4ETDP1PARP1 | |
| SCHEMBL30172555 | 0.68 | KDM4E (0.63) | KDM4EALDH1A1POLBGAATDP1 | |
| SCHEMBL8729784 | 0.68 | KDM4E (0.63) | KDM4EALDH1A1POLBGAATDP1 | |
| SCHEMBL29804928 | 0.68 | PARP1 (0.46) | PDPK1DAOKDM4ETDP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | IDEAYA BIOSCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220227780-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. | 2022-07-21 | — | — | US | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | ERG28, DPM1, CYP51A1 | PDPK1 1851/4885DAO 59/4885KDM4E 3245/4885 |
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | DHFR, CYC1, CYCS | PDPK1 1441/4885DAO 2633/4885KDM4E 3956/4885 |
| US-20220227780-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | DHFR, CYC1, CYCS | PDPK1 1441/4885DAO 2633/4885KDM4E 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.