Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301445 | 0.79 | KDM4E (0.45) | KDM4EMAPTMEN1KMT2AP2RY14 | |
| SCHEMBL7267112 | 0.78 | HTR3E (0.45) | KDM4EMAPTCHRNA7MEN1KMT2A | |
| SCHEMBL7273067 | 0.78 | HTR3E (0.45) | KDM4EMAPTCHRNA7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7301304 | 0.78 | KDM4E (0.44) | KDM4EMAPTMEN1KMT2AP2RY14 | |
| SCHEMBL7295880 | 0.73 | AKR1C4 (0.44) | CHRNA7ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7324702 | 0.73 | KDM4E (0.37) | KDM4EMAPTMETAP2MEN1GAPDH | |
| SCHEMBL27536215 | 0.71 | ACMSD (0.46) | KDM4EMAPTCSNK2A1NOTUM | |
| SCHEMBL27516462 | 0.69 | ACMSD (0.47) | KDM4EMAPTKMT2ATDP1L3MBTL1 | |
| SCHEMBL27866187 | 0.68 | MAPT (0.45) | KDM4EMAPTPOLBNOTUMALDH1A1 | |
| SCHEMBL28060311 | 0.66 | MAPT (0.39) | MAPTKMT2ANOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |