Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7321944 | 0.99 | SLC6A3 (0.67) | SLC6A3DRD2DRD4CHRM4 | |
| SCHEMBL466899 | 0.86 | SIGMAR1 (0.68) | — | |
| Hydrochloric Acid SCHEMBL7321403 | 0.86 | KCNH2 (0.73) | DRD2 | |
| SCHEMBL7325179 | 0.85 | SLC6A4 (0.71) | SLC6A3DRD2 | |
| Hydrochloric Acid SCHEMBL7319263 | 0.84 | SLC6A4 (0.69) | SLC6A3DRD2 | |
| Hydrochloric Acid SCHEMBL7326254 | 0.83 | SLC6A4 (0.65) | SLC6A3DRD2 | |
| SCHEMBL17831090 | 0.83 | ADIPOR2 (0.64) | DRD2DRD4CHRM4 | |
| SCHEMBL15767968 | 0.82 | SLC6A3 (0.69) | SLC6A3 | |
| SCHEMBL1334144 | 0.82 | DRD2 (0.69) | SLC6A3DRD2 | |
| SCHEMBL9561754 | 0.81 | SLC6A3 (0.63) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169855-A | PIPERIDINE ETHER DERIVATIVES AS PSYCHOTROPIC DRUGS OR PLANT FUNGICIDES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | claimed |
| JP-4356462-A | — | — | None | — | — | JP | disclosed |
| US-6303593-B1 | FOR THERAPY HUMAN IMMUNODEFICIENCY VIRUS INFECTION, AQUIRED IMMUNODEFICIENCY SYNDROME (AIDS), INFLAMMATORY AND IMMUNOREGULATORY DISORDER OR DISEASE, ASTHMA, ALLERGIC RHINITIS, DERMATITIS, CONJUNCTIVITIS, ATHEROSCLEROSIS | MERCK & CO., INC. | 2001-10-16 | — | — | US | disclosed |
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| JP-H04356462-A | PIPERIDINE ETHER DERIVATIVE AS PSYCHOTROPIC DRUG OR PLANT FUNGICIDE | DU PONT MERCK PHARMACEUT CO | 1992-12-10 | — | — | JP | disclosed |
| US-5169855-A | PIPERIDINE ETHER DERIVATIVES AS PSYCHOTROPIC DRUGS OR PLANT FUNGICIDES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| CN-1061963-A | Be used as the croak pyridine class of the 4-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-06-17 | — | — | CN | disclosed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |