Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307240 | 0.84 | ITGB3 (0.54) | MTNR1A | |
| SCHEMBL7297144 | 0.80 | MTNR1A (0.63) | MTNR1ATP53 | |
| SCHEMBL6958873 | 0.80 | ITGB3 (0.55) | MAOBRAB9AMAOAACHESMPD1 | |
| SCHEMBL7297084 | 0.79 | ITGB3 (0.56) | RAB9A | |
| SCHEMBL7307505 | 0.79 | ITGB3 (0.49) | RAB9ATP53 | |
| SCHEMBL7300468 | 0.78 | RAB9A (0.44) | MAOBRAB9AMAOASMPD1KCNH2 | |
| SCHEMBL7302536 | 0.78 | MTNR1A (0.45) | RAB9AMTNR1ATP53 | |
| SCHEMBL6554181 | 0.74 | MTNR1A (0.44) | RAB9AMAOAMTNR1ATP53 | |
| SCHEMBL6555465 | 0.74 | MTNR1A (0.44) | RAB9AMAOAMTNR1ATP53 | |
| SCHEMBL6553963 | 0.74 | MTNR1A (0.44) | RAB9AMAOAMTNR1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |