Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 6/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269532 | 1.00 | MAPT (0.54) | MAPTNPC1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9273979 | 0.99 | MAPT (0.53) | MAPTNPC1LMNAMEN1KMT2A | |
| Acetic Acid SCHEMBL9274305 | 0.97 | NPC1 (0.51) | MAPTNPC1LMNAMEN1KMT2A | |
| SCHEMBL9274240 | 0.88 | MAPT (0.52) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7303187 | 0.88 | ITGB3 (0.56) | NPC1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7303301 | 0.88 | ITGB3 (0.56) | NPC1LMNAMEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL9261540 | 0.87 | MAPT (0.51) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7442551 | 0.86 | PRSS1 (0.61) | NPC1LMNAMEN1KMT2ACA12 | |
| SCHEMBL5037610 | 0.81 | PKM (0.49) | MAPTNPC1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8407192 | 0.81 | PRSS1 (0.54) | MAPTKMT2AGAAF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |