Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310586 | 0.83 | TSHR (0.45) | HPGDTSHRGAACHRM1KMT2A | |
| SCHEMBL10421850 | 0.73 | TSHR (0.52) | HPGDTSHRGAACHRM1KMT2A | |
| SCHEMBL10420620 | 0.72 | TSHR (0.50) | HPGDTSHRGAACHRM1KMT2A | |
| SCHEMBL6952090 | 0.71 | ADORA1 (0.46) | DPP7 | |
| SCHEMBL10420636 | 0.70 | DPP7 (0.53) | HPGDTSHRGAACHRM1KMT2A | |
| SCHEMBL1797490 | 0.68 | CTSS (0.47) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1797492 | 0.68 | CTSS (0.47) | CTSSCTSLCTSBCTSK | |
| SCHEMBL23879177 | 0.67 | CTSL (0.45) | HPGDTSHRGAAKMT2ACTSS | |
| SCHEMBL6350465 | 0.67 | KMT2A (0.66) | KMT2AMAPK1CTSSCTSLCTSB | |
| SCHEMBL3271144 | 0.66 | REN (0.40) | HPGDTSHRGAACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508220-B1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE AG (DE) | 1995-07-26 | — | — | EP | disclosed |
| US-5274098-A | Amidinophenylalanine derivatives, process for their preparation, their use and compositions containing them | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0508220-A1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-10-14 | — | — | EP | disclosed |