Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.47 |
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797492 | 1.00 | CTSS (0.47) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL8838179 | 0.83 | CTSS (0.46) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL7310586 | 0.83 | TSHR (0.45) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8392929 | 0.82 | ATM (0.45) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL9321962 | 0.82 | ATM (0.45) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL11651226 | 0.82 | ATM (0.45) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL1310667 | 0.81 | ITGA4 (0.44) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL11888719 | 0.81 | ITGA4 (0.44) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL2476924 | 0.81 | MMP13 (0.46) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL1401042 | 0.81 | MMP13 (0.46) | CTSSCTSKCTSBCTSLITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5097793-A | — | — | None | — | — | JP | disclosed |
| US-7951943-B2 | Method for preparing and purifying 3-hydroxyamidinophenylalanine compounds | WILEX AG (DE) | 2011-05-31 | — | — | US | disclosed |
| EP-1799665-B1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2009-08-19 | — | — | EP | disclosed |
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1799665-A1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | Wilex AG (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006042678-A1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2006-04-27 | — | — | WO | disclosed |
| EP-0508220-B1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE AG (DE) | 1995-07-26 | — | — | EP | disclosed |
| US-5274098-A | Amidinophenylalanine derivatives, process for their preparation, their use and compositions containing them | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| JP-H0597793-A | AMIDINOPHENYLALANINE DERIVATIVE | BEHRINGWERKE AG | 1993-04-20 | — | — | JP | disclosed |
| EP-0508220-A1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | PEPD, PAH, PRSS3 | CTSS 81/4885CTSK 206/4885CTSB 363/4885 |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | PEPD, PAH, PRSS3 | CTSS 81/4885CTSK 206/4885CTSB 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.