SCHEMBL7302819

SCHEMBL7302819

CCOC(=O)[C@H]1NCC(=S)C1C(=O)[C@@H]1CCCN1C(=O)CCCC1=Cc2cc(N)c(C)cc2C1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7302892 0.82 PREP (0.42) PREPALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL7301966 0.73 HTR1A (0.34) ALDH1A1KDM4E
SCHEMBL7293185 0.73 TSHR (0.36) PREPALDH1A1KDM4ESMN1; SMN2
SCHEMBL7302389 0.70 PREP (0.47) PREP
SCHEMBL9049670 0.68 PREP (0.47) PREP
SCHEMBL9049709 0.68 PREP (0.46) PREP
SCHEMBL7292870 0.67 PREP (0.53) PREPALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL7303962 0.67 PREP (0.66) PREP
SCHEMBL7303965 0.67 PREP (0.66) PREP
SCHEMBL7301136 0.67 MEN1 (0.32) ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed