Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301966 | 0.82 | HTR1A (0.34) | MAPK1ALDH1A1HTR1AHTR7MAPT | |
| SCHEMBL7301136 | 0.74 | MEN1 (0.32) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9048219 | 0.74 | PREP (0.43) | HTR1AHTR7PREP | |
| SCHEMBL7302892 | 0.73 | PREP (0.42) | ALDH1A1HTR1AHTR7CPT2CPT1A | |
| SCHEMBL7302819 | 0.73 | PREP (0.31) | ALDH1A1PREPKDM4ESMN1; SMN2 | |
| SCHEMBL9046582 | 0.71 | PREP (0.44) | HTR1AHTR7PREP | |
| SCHEMBL7294376 | 0.70 | ALDH1A1 (0.32) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9046480 | 0.68 | PREP (0.46) | PREPF2 | |
| SCHEMBL9048411 | 0.68 | PREP (0.46) | PREPF2 | |
| SCHEMBL9049491 | 0.68 | PREP (0.45) | PREPF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |