Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 2/20 | 0.44 |
| ▸ | MMP7 known ✓ | P09237 | 2/20 | 0.44 |
| ▸ | MMP13 known ✓ | P45452 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7302838 | 0.96 | F2 (0.50) | F2HPGDMMP1MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL7293874 | 0.82 | F2 (0.48) | F2HPGDGAASLC6A9SLC6A5 | |
| SCHEMBL8423661 | 0.81 | CTSG (0.54) | C3AR1LMNAALBL3MBTL1NPY1R | |
| SCHEMBL8069663 | 0.81 | C3AR1 (0.47) | HPGDGAAC3AR1LMNAALB | |
| SCHEMBL31751570 | 0.80 | C3AR1 (0.43) | F2C3AR1SLC6A5QRFPRNPY1R | |
| SCHEMBL7786354 | 0.79 | FOLH1 (0.49) | C3AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7786368 | 0.79 | FOLH1 (0.49) | C3AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7442230 | 0.79 | C3AR1 (0.62) | HPGDMMP1MMP2MMP3MMP7 | |
| SCHEMBL7471967 | 0.79 | C3AR1 (0.62) | HPGDMMP1MMP2MMP3MMP7 | |
| SCHEMBL4407484 | 0.79 | C3AR1 (0.53) | HPGDGAAC3AR1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |