Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 2/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | MMP7 | P09237 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442230 | 1.00 | C3AR1 (0.62) | C3AR1MMP1MMP2MMP3MMP7 | |
| SCHEMBL8423661 | 0.83 | CTSG (0.54) | C3AR1ITGB3ITGA2BL3MBTL1LMNA | |
| SCHEMBL9109669 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BPIN1GRIA1CHRNB2 | |
| SCHEMBL9109661 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BPIN1GRIA1CHRNB2 | |
| SCHEMBL19418929 | 0.82 | PIN1 (0.54) | C3AR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL5273134 | 0.82 | KMT2A (0.57) | C3AR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL28229751 | 0.82 | KMT2A (0.57) | C3AR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL24533898 | 0.82 | PIN1 (0.59) | ITGB3ITGA2BPIN1 | |
| Hydrochloric Acid SCHEMBL7302838 | 0.82 | F2 (0.50) | C3AR1MMP1MMP2MMP3MMP7 | |
| SCHEMBL9829269 | 0.81 | FOLH1 (0.54) | MMP2MMP3MMP9MMP13ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | claimed |