Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078211 | 0.88 | PLAAT3 (0.49) | KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8064045 | 0.86 | C3AR1 (0.55) | C3AR1CNR1 | |
| SCHEMBL8423661 | 0.85 | CTSG (0.54) | C3AR1L3MBTL1ALBLMNA | |
| Hydrochloric Acid SCHEMBL7302838 | 0.84 | F2 (0.50) | C3AR1L3MBTL1GAAHPGDALB | |
| SCHEMBL7786368 | 0.83 | FOLH1 (0.49) | C3AR1RAB9A | |
| SCHEMBL7786354 | 0.83 | FOLH1 (0.49) | C3AR1RAB9A | |
| SCHEMBL21722102 | 0.83 | GGT1 (0.61) | C3AR1L3MBTL1F10GAAHPGD | |
| SCHEMBL4407484 | 0.83 | C3AR1 (0.53) | C3AR1GAAHPGDCNR1 | |
| SCHEMBL10277213 | 0.83 | C3AR1 (0.53) | C3AR1GAAHPGDCNR1 | |
| SCHEMBL30139852 | 0.81 | C3AR1 (0.51) | C3AR1F10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017664-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015490-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | disclosed |