Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308221 | 0.92 | PARP1 (0.63) | PARP1SIGMAR1 | |
| SCHEMBL7307656 | 0.88 | PARP1 (0.63) | PARP1DRD2 | |
| SCHEMBL7307433 | 0.88 | PARP1 (0.62) | PARP1SIGMAR1 | |
| SCHEMBL7305161 | 0.88 | PARP1 (0.73) | PARP1 | |
| Bromide SCHEMBL7309634 | 0.87 | PARP1 (0.62) | PARP1DRD2 | |
| Hydrochloric Acid SCHEMBL7301868 | 0.87 | PARP1 (0.62) | PARP1 | |
| SCHEMBL7303980 | 0.86 | PARP1 (0.60) | PARP1 | |
| SCHEMBL7303316 | 0.85 | PARP1 (0.64) | PARP1DRD2 | |
| SCHEMBL7301646 | 0.85 | PARP1 (0.59) | PARP1SIGMAR1 | |
| Bromide SCHEMBL7303725 | 0.84 | PARP1 (0.63) | PARP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |