SCHEMBL7303101

SCHEMBL7303101

Nc1c[n+]([O-])c2c(c1[N+](=O)[O-])COCC2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307200 0.79 ACHE (0.31)
SCHEMBL7300045 0.71
SCHEMBL7307619 0.68 RAB9A (0.34) MAPT
SCHEMBL10377637 0.62 ALDH1A1 (0.36)
SCHEMBL8566829 0.59 MAPT (0.43) MAPT
SCHEMBL10818074 0.59 MAPT (0.44) MAPT
SCHEMBL17008811 0.57 PTGER4 (0.31)
SCHEMBL2251607 0.57 MAPT (0.41) MAPT
SCHEMBL4825728 0.55 LIMK1 (0.35)
SCHEMBL2245425 0.54 GRIN2D (0.44) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556008-B1 Condensed imidazopyridine derivatives with psychotropic activity SHIONOGI & CO (JP) 1997-05-14 EP disclosed
US-5461062-A Psychotropic agent as antianxiety agent, anesthesia antagonistic agent SHIONOGI & CO., LTD. (JP) 1995-10-24 US disclosed
US-5378848-A Benzodiazepine agonist, psychotropic, antianxiety, cerebral function activator, anesthesia atagonist SHIONOGI & CO., LTD. (JP) 1995-01-03 US disclosed
EP-0556008-A1 Condensed imidazopyridine derivatives with psychotropic activity SHIONOGI & CO., LTD. (JP) 1993-08-18 EP disclosed