Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286290 | 0.80 | MAPT (0.43) | MAPTNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL3342318 | 0.80 | TSHR (0.51) | MAPTNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL10683266 | 0.80 | CYP3A4 (0.41) | MAPTNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL9770616 | 0.73 | ALDH1A1 (0.44) | MAPTNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL9770602 | 0.72 | CTSB (0.49) | MAPTKDM4EHTTLMNAMITF | |
| SCHEMBL10690547 | 0.70 | MAPT (0.51) | MAPTNPC1RAB9AKDM4EHTT | |
| SCHEMBL9770618 | 0.70 | CTSB (0.53) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL10688327 | 0.68 | S100A4 (0.36) | MAPTNPSR1NPC1RAB9AKDM4E | |
| SCHEMBL2026504 | 0.68 | TSHR (0.62) | CYP3A4LMNAS100A4TSHRMEN1 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL21114410 | 0.67 | MAPT (0.56) | MAPTNPSR1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089757-C | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 2002-08-28 | — | — | CN | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |