Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303256 | 0.86 | SLC7A5 (0.48) | SLC7A5MEN1ALOX15KMT2ABLM | |
| SCHEMBL11225485 | 0.84 | SLC7A5 (0.54) | SLC7A5ALDH1A1SLC1A3SLC1A2ANPEP | |
| SCHEMBL11225491 | 0.84 | SLC7A5 (0.54) | SLC7A5ALDH1A1SLC1A3SLC1A2ANPEP | |
| SCHEMBL12857274 | 0.82 | SLC7A5 (0.48) | SLC7A5CHRM2CHRM4CHRM1LTA4H | |
| SCHEMBL15840411 | 0.81 | PAOX (0.47) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL11048596 | 0.80 | SLC7A5 (0.50) | SLC7A5ALOX15KMT2ABLMCHRM2 | |
| SCHEMBL13705504 | 0.79 | LMNA (0.46) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL17029472 | 0.78 | GSR (0.59) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL260557 | 0.77 | PAOX (0.56) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL13300751 | 0.77 | PAOX (0.56) | PAOXMEN1ALDH1A1PLGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |