Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311107 | 0.95 | HTR2B (0.38) | HTR2BSIGMAR1 | |
| SCHEMBL7311231 | 0.92 | HTR2B (0.36) | HTR2BUSP30 | |
| SCHEMBL7314926 | 0.91 | HTR2B (0.40) | HTR2BUSP30DRD2 | |
| SCHEMBL7316515 | 0.89 | HTR2B (0.35) | HTR2BSIGMAR1DRD2 | |
| SCHEMBL7303264 | 0.87 | HTR2B (0.38) | HTR2BUSP30DRD2 | |
| SCHEMBL7316461 | 0.86 | DRD2 (0.34) | HTR2BSIGMAR1KCNA3DRD2 | |
| SCHEMBL7310427 | 0.86 | HTR2B (0.43) | HTR2BUSP30 | |
| SCHEMBL7308728 | 0.86 | SIGMAR1 (0.34) | HTR2BSIGMAR1KCNA3 | |
| SCHEMBL7316507 | 0.85 | FAAH (0.33) | SIGMAR1DRD2 | |
| SCHEMBL7309520 | 0.84 | SIGMAR1 (0.36) | HTR2BSIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |