Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777316 | 0.88 | DRD1 (0.51) | DRD1PPIDPTPN1MMEANPEP | |
| SCHEMBL7294526 | 0.80 | LCK (0.41) | PPIDTACR1LCK | |
| SCHEMBL7302581 | 0.78 | ALDH1A1 (0.43) | PPIDTACR1LMNALCK | |
| SCHEMBL7296838 | 0.77 | PPID (0.41) | PPIDLCK | |
| SCHEMBL9816930 | 0.77 | DRD1 (0.54) | DRD1PTPN1PTPN2LMNAATM | |
| SCHEMBL9816924 | 0.77 | DRD1 (0.54) | DRD1PTPN1PTPN2LMNAATM | |
| SCHEMBL752327 | 0.77 | DRD1 (0.50) | DRD1PPIDL3MBTL1FNTAFNTB | |
| SCHEMBL28016251 | 0.77 | DRD1 (0.50) | DRD1PPIDL3MBTL1FNTAFNTB | |
| SCHEMBL9816922 | 0.74 | ATM (0.53) | DRD1PTPN1MMEHPGDLMNA | |
| SCHEMBL9816929 | 0.74 | ATM (0.53) | DRD1PTPN1MMEHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393781-B1 | Dopamine pro-drug | ZAMBON SPA (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |