Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.37 |
| ▸ | IARS1 | P41252 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296838 | 0.89 | PPID (0.41) | LCKALDH1A1PPID | |
| SCHEMBL7294519 | 0.87 | GRB2 (0.46) | LCKALDH1A1ALOX15ALOX12EGFR | |
| SCHEMBL7302581 | 0.86 | ALDH1A1 (0.43) | LCKALDH1A1ALOX15ALOX12EGFR | |
| SCHEMBL7295209 | 0.81 | ALOX15 (0.46) | LCKALDH1A1ALOX15ALOX12EGFR | |
| SCHEMBL7303478 | 0.80 | DRD1 (0.53) | LCKPPIDTACR1 | |
| SCHEMBL9777176 | 0.79 | CAPN1 (0.54) | — | |
| SCHEMBL7296829 | 0.79 | GRB2 (0.47) | LCKPPID | |
| SCHEMBL11850734 | 0.78 | LCK (0.53) | LCKALDH1A1ALOX15ALOX12EGFR | |
| SCHEMBL7298903 | 0.77 | LCK (0.42) | LCKALDH1A1EGFRPPIDMAPT | |
| SCHEMBL10953335 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TACR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393781-B1 | Dopamine pro-drug | ZAMBON SPA (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |
| EP-0393781-A2 | Dopamine pro-drug | ZAMBON GROUP S.p.A. (IT) | 1990-10-24 | — | — | EP | disclosed |