Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303856 | 0.93 | MAPK1 (0.39) | GLAHTR2BHRH3MAPK1L3MBTL1 | |
| SCHEMBL7309051 | 0.90 | HTR2B (0.39) | HTR2BHRH3MAPK1L3MBTL1HRH4 | |
| SCHEMBL7306892 | 0.88 | SMN1; SMN2 (0.41) | HTR2BHRH3L3MBTL1SIGMAR1 | |
| SCHEMBL7314624 | 0.87 | HTR2B (0.39) | GLAHTR2BHRH3MAPK1L3MBTL1 | |
| SCHEMBL7301308 | 0.85 | HTR2B (0.35) | GLAHTR2BMAPK1L3MBTL1MAOA | |
| SCHEMBL7312749 | 0.85 | HTR2B (0.36) | GLAHTR2BMAPK1L3MBTL1 | |
| SCHEMBL7311133 | 0.84 | MAPK1 (0.41) | GLAHTR2BHRH3MAPK1L3MBTL1 | |
| SCHEMBL7308028 | 0.84 | MAPK1 (0.39) | GLAHTR2BMAPK1L3MBTL1TERT | |
| SCHEMBL7317110 | 0.84 | SIGMAR1 (0.47) | HTR2BSIGMAR1 | |
| SCHEMBL7303812 | 0.83 | MAOA (0.36) | GLAHTR2BHRH3MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |