Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291413 | 0.81 | SMN1; SMN2 (0.76) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7302094 | 0.81 | SMN1; SMN2 (0.76) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7296019 | 0.80 | MAPT (0.64) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7301498 | 0.79 | NR1H4 (0.56) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL18539815 | 0.77 | POLB (0.38) | SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL7303735 | 0.76 | NR1H4 (0.47) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7295416 | 0.76 | ALDH1A1 (0.52) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7295360 | 0.76 | NR1H4 (0.60) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6029460 | 0.75 | KDM4E (0.53) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7303695 | 0.74 | NPC1 (0.54) | NR1H4MAPTNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |