Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LIG1 | P18858 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029460 | 0.86 | KDM4E (0.53) | NPC1RAB9AALDH1A1NR1H4MAPT | |
| SCHEMBL7303735 | 0.84 | NR1H4 (0.47) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL7295416 | 0.84 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1GAANR1H4 | |
| SCHEMBL7300821 | 0.84 | RAB9A (0.66) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL7297398 | 0.83 | SERPINE1 (0.54) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL13762076 | 0.80 | MLYCD (0.70) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL10631908 | 0.78 | BRD4 (0.61) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL30428722 | 0.78 | BRD4 (0.61) | NPC1RAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL7296019 | 0.78 | MAPT (0.64) | NPC1RAB9AALDH1A1GAANR1H4 | |
| SCHEMBL5315452 | 0.78 | RAB9A (0.70) | NPC1RAB9AALDH1A1GLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |