Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295416 | 0.91 | ALDH1A1 (0.52) | NR1H4ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7303695 | 0.84 | NPC1 (0.54) | NR1H4ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL6029460 | 0.83 | KDM4E (0.53) | NR1H4ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7301498 | 0.81 | NR1H4 (0.56) | NR1H4ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7297398 | 0.81 | SERPINE1 (0.54) | NR1H4ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7303513 | 0.76 | NR1H4 (0.52) | NR1H4RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL7302035 | 0.76 | NR1H4 (0.67) | NR1H4ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL7292413 | 0.74 | HSD17B2 (0.58) | NR1H4ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7291413 | 0.74 | SMN1; SMN2 (0.76) | NR1H4ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7302094 | 0.74 | SMN1; SMN2 (0.76) | NR1H4ALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |