SCHEMBL7303792

SCHEMBL7303792

CCOC(=O)CCCCc1ccc(C(=N)NC(=O)OCc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
CASP1 P29466 2/20 0.47
CYP4Z1 Q86W10 2/20 0.47
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
MAPK1 P28482 2/20 0.43
LTA4H P09960 2/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
F2 P00734 1/20 0.43
CYP4F11 Q9HBI6 1/20 0.42
CYP4F12 Q9HCS2 1/20 0.42
MASP2 O00187 1/20 0.42
POLB P06746 1/20 0.41
DPP4 P27487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7301104 0.92 CASP1 (0.49) ALOX5CASP1CYP4Z1CYP4F2CYP4A11
SCHEMBL7293967 0.87 LTA4H (0.54) LTA4H
SCHEMBL7295145 0.86 LTA4H (0.53) LTA4H
SCHEMBL7296429 0.86 LTA4H (0.53) LTA4H
SCHEMBL7294390 0.86 LTA4H (0.53) LTA4HTDP1POLB
SCHEMBL2771639 0.85 ALDH1A1 (0.52) CASP1CYP4Z1MAPK1F2MASP2
SCHEMBL27342967 0.82 NPC1 (0.53) ALOX5CASP1CYP4Z1CYP4F2CYP4A11
SCHEMBL7302595 0.81 FFAR1 (0.52) CASP1F2
SCHEMBL14161303 0.81 MAPT (0.54) GAATDP1F2MASP2
SCHEMBL8363489 0.80 NPC1 (0.50) TDP1MASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5574016-A Peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-12 US disclosed
EP-0513675-B1 New peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-09-11 EP disclosed
EP-0513675-A1 New peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed