SCHEMBL7295145

SCHEMBL7295145

CCOC(=O)CCCCCCCOc1ccc(C(=N)NC(=O)OCc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 11/20 0.53
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ITGB3 P05106 4/20 0.46
ITGA2B P08514 4/20 0.46
CYSLTR2 Q9NS75 1/20 0.46
CYSLTR1 Q9Y271 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7296429 1.00 LTA4H (0.53) LTA4HMAPTL3MBTL1ITGB3ITGA2B
SCHEMBL7293967 0.99 LTA4H (0.54) LTA4HMAPTL3MBTL1ITGB3ITGA2B
SCHEMBL7294390 0.96 LTA4H (0.53) LTA4HMAPTL3MBTL1CYSLTR2CYSLTR1
SCHEMBL7297510 0.88 PPARA (0.54) LTA4HMAPTL3MBTL1ITGB3ITGA2B
SCHEMBL7302236 0.88 PPARA (0.54) LTA4HMAPTL3MBTL1ITGB3ITGA2B
SCHEMBL8177159 0.87 ITGB3 (0.51) MAPTL3MBTL1ITGB3ITGA2B
SCHEMBL7302421 0.87 PPARA (0.55) LTA4HMAPTL3MBTL1ITGB3ITGA2B
SCHEMBL14367308 0.87 L3MBTL1 (0.55) MAPTL3MBTL1ITGB3ITGA2B
SCHEMBL7303792 0.86 ALOX5 (0.48) LTA4H
SCHEMBL8175391 0.86 ITGB3 (0.49) MAPTL3MBTL1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5574016-A Peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-12 US disclosed
EP-0513675-B1 New peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-09-11 EP disclosed
EP-0513675-A1 New peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed