Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.77 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299921 | 0.87 | SIGMAR1 (1.00) | SIGMAR1ACHEHTR1AHTR2BDRD2 | |
| SCHEMBL7297159 | 0.85 | SIGMAR1 (0.81) | SIGMAR1ACHEHTR1AHTR2BDRD2 | |
| SCHEMBL466945 | 0.82 | SIGMAR1 (0.76) | SIGMAR1ACHEHTR1AHTR2BSMN1; SMN2 | |
| SCHEMBL7300222 | 0.81 | SIGMAR1 (0.70) | SIGMAR1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7305898 | 0.81 | SIGMAR1 (0.77) | SIGMAR1ACHEHTR1AHTR2BSMN1; SMN2 | |
| SCHEMBL7302990 | 0.80 | SIGMAR1 (0.68) | SIGMAR1ACHEHTR1AHTR2BPOLB | |
| SCHEMBL7294524 | 0.80 | SIGMAR1 (0.76) | SIGMAR1ACHEHTR1AHTR2BPOLB | |
| SCHEMBL8946225 | 0.80 | SIGMAR1 (0.75) | SIGMAR1ACHEHTR1AHTR2BSMN1; SMN2 | |
| SCHEMBL17237763 | 0.79 | SIGMAR1 (0.75) | SIGMAR1ACHEHTR1AHTR2BSMN1; SMN2 | |
| SCHEMBL7298240 | 0.79 | SIGMAR1 (0.75) | SIGMAR1ACHEHTR1AHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | claimed |
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |