Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308195 | 0.90 | LMNA (0.48) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7305114 | 0.78 | CYP2A6 (0.50) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2043221 | 0.76 | CHRM2 (0.49) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL8557526 | 0.76 | LMNA (0.62) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL5034245 | 0.75 | CSNK2A1 (0.43) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL4961151 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL1835382 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL29712151 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL8220033 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL2686471 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |