Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 9/20 | 0.37 |
| ▸ | CTSL | P07711 | 8/20 | 0.37 |
| ▸ | CTSS | P25774 | 7/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304749 | 0.97 | CTSC (0.41) | CTSCCTSKCTSLCTSSCTSB | |
| SCHEMBL7304203 | 0.87 | CTSC (0.45) | CTSC | |
| SCHEMBL7283568 | 0.87 | CASP1 (0.43) | CTSLCTSBCASP1 | |
| SCHEMBL7275336 | 0.84 | CASP1 (0.41) | CTSBCASP1 | |
| SCHEMBL7417508 | 0.83 | CASP1 (0.35) | CTSLLNPEPERAP2ERAP1CASP1 | |
| SCHEMBL7304440 | 0.83 | F2 (0.38) | CTSCCTSKCTSBLNPEPERAP2 | |
| SCHEMBL7301728 | 0.82 | CTSC (0.47) | CTSCCTSKCTSLCTSSCYP1A2 | |
| SCHEMBL7416641 | 0.81 | CASP1 (0.34) | LNPEPERAP2ERAP1CASP1 | |
| SCHEMBL7283411 | 0.73 | CASP1 (0.47) | CASP1 | |
| SCHEMBL7296845 | 0.71 | GNPAT (0.47) | CTSCCTSKCTSLCTSSCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547699-A1 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO. INC. (US) | 1993-06-23 | — | — | EP | disclosed |