Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 13/20 | 0.44 |
| ▸ | PLG | P00747 | 6/20 | 0.44 |
| ▸ | PLAT | P00750 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304440 | 0.93 | F2 (0.38) | CTSCF2PLGPLATPRSS1 | |
| SCHEMBL7303940 | 0.87 | CTSC (0.43) | CTSC | |
| SCHEMBL7301728 | 0.86 | CTSC (0.47) | CTSC | |
| SCHEMBL7283411 | 0.85 | CASP1 (0.47) | F2PLGPLATPRSS1F10 | |
| SCHEMBL7304749 | 0.85 | CTSC (0.41) | CTSC | |
| SCHEMBL7423470 | 0.81 | F2 (0.41) | F2PLGPLATPRSS1F10 | |
| SCHEMBL7286570 | 0.79 | CASP1 (0.40) | F2PLGPLATPRSS1F10 | |
| SCHEMBL7424734 | 0.75 | ERAP2 (0.36) | F2PLGPLATPRSS1F10 | |
| SCHEMBL7277260 | 0.71 | CASP1 (0.41) | — | |
| SCHEMBL7285059 | 0.71 | CASP3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547699-A1 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO. INC. (US) | 1993-06-23 | — | — | EP | disclosed |