Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202736 | 0.85 | LTA4H (0.55) | LTA4HHTTSLC1A3SLC1A1ANPEP | |
| SCHEMBL9202741 | 0.85 | LTA4H (0.55) | LTA4HHTTSLC1A3SLC1A1ANPEP | |
| SCHEMBL5906855 | 0.84 | CTRB1 (0.54) | SLC1A3SLC1A1CA12CA1CA2 | |
| SCHEMBL5906852 | 0.84 | CTRB1 (0.54) | SLC1A3SLC1A1CA12CA1CA2 | |
| SCHEMBL9195808 | 0.84 | LTA4H (0.60) | LTA4HSLC1A3SLC1A1ANPEPECE1 | |
| SCHEMBL9195814 | 0.84 | LTA4H (0.60) | LTA4HSLC1A3SLC1A1ANPEPECE1 | |
| SCHEMBL11190557 | 0.83 | CTRB1 (0.56) | HTTSLC1A3SLC1A1CA12CA1 | |
| SCHEMBL5160238 | 0.82 | SLC1A3 (0.47) | LTA4HHTTSLC1A3SLC1A1ANPEP | |
| SCHEMBL36610 | 0.82 | SLC1A3 (0.47) | LTA4HHTTSLC1A3SLC1A1ANPEP | |
| SCHEMBL561573 | 0.82 | LTA4H (0.56) | LTA4HHTTSLC1A3SLC1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |