Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202741 | 1.00 | LTA4H (0.55) | LTA4HANPEPMMP2SLC1A3SLC1A1 | |
| SCHEMBL9195808 | 0.96 | LTA4H (0.60) | LTA4HANPEPMMP2SLC1A3SLC1A1 | |
| SCHEMBL9195814 | 0.96 | LTA4H (0.60) | LTA4HANPEPMMP2SLC1A3SLC1A1 | |
| SCHEMBL7303955 | 0.85 | LTA4H (0.58) | LTA4HANPEPSLC1A3SLC1A1CA12 | |
| Hydrochloric Acid SCHEMBL10653391 | 0.83 | LTA4H (0.53) | LTA4HANPEPMMP2SLC1A3SLC1A1 | |
| SCHEMBL5906855 | 0.83 | CTRB1 (0.54) | SLC1A3SLC1A1CA12CA1CA2 | |
| SCHEMBL5906852 | 0.83 | CTRB1 (0.54) | SLC1A3SLC1A1CA12CA1CA2 | |
| SCHEMBL4622400 | 0.83 | LTA4H (0.52) | LTA4HANPEPMMP2SLC1A3SLC1A1 | |
| SCHEMBL20335061 | 0.83 | LTA4H (0.52) | LTA4HANPEPMMP2SLC1A3SLC1A1 | |
| SCHEMBL11190557 | 0.82 | CTRB1 (0.56) | MMP2SLC1A3SLC1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |