Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195814 | 1.00 | LTA4H (0.60) | LTA4HMMP2ANPEPDPP8DPP7 | |
| SCHEMBL9202736 | 0.96 | LTA4H (0.55) | LTA4HMMP2ANPEPDPP8DPP7 | |
| SCHEMBL9202741 | 0.96 | LTA4H (0.55) | LTA4HMMP2ANPEPDPP8DPP7 | |
| Hydrochloric Acid SCHEMBL10653391 | 0.87 | LTA4H (0.53) | LTA4HMMP2ANPEPDPP8DPP7 | |
| SCHEMBL7303955 | 0.84 | LTA4H (0.58) | LTA4HANPEPECE1CPB1SLC1A3 | |
| SCHEMBL16495147 | 0.83 | ECE1 (0.56) | LTA4HMMP2ECE1CPB1CPB2 | |
| SCHEMBL676143 | 0.83 | LTA4H (0.57) | LTA4HMMP2ANPEPDPP8DPP7 | |
| SCHEMBL730307 | 0.83 | LTA4H (0.57) | LTA4HMMP2ANPEPDPP8DPP7 | |
| SCHEMBL2289331 | 0.82 | LTA4H (0.58) | LTA4HMMP2ANPEPECE1CPB1 | |
| SCHEMBL18567745 | 0.82 | MMP2 (0.60) | LTA4HMMP2ANPEPDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |