Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298376 | 0.92 | SIGMAR1 (0.60) | SIGMAR1HTR1ADRD2HTR2BKDM4E | |
| SCHEMBL7299897 | 0.87 | SIGMAR1 (0.62) | SIGMAR1HTR1ADRD2HTR2BKDM4E | |
| SCHEMBL7294373 | 0.85 | SIGMAR1 (0.60) | SIGMAR1HTR1ADRD2HTR2BKDM4E | |
| SCHEMBL466945 | 0.84 | SIGMAR1 (0.76) | SIGMAR1HTR1ADRD2HTR2BKDM4E | |
| SCHEMBL7299375 | 0.81 | SIGMAR1 (0.69) | SIGMAR1HTR1ADRD2HTR2BPOLB | |
| SCHEMBL3398900 | 0.81 | HTR1A (0.65) | SIGMAR1HTR1ADRD2HTR2BKDM4E | |
| SCHEMBL8946184 | 0.78 | SIGMAR1 (0.65) | SIGMAR1HTR1ADRD2HTR2BPOLB | |
| SCHEMBL7294524 | 0.78 | SIGMAR1 (0.76) | SIGMAR1HTR1ADRD2HTR2BPOLB | |
| SCHEMBL7305898 | 0.76 | SIGMAR1 (0.77) | SIGMAR1HTR1AHTR2BKDM4EALDH1A1 | |
| SCHEMBL7302990 | 0.76 | SIGMAR1 (0.68) | SIGMAR1HTR1AHTR2BPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |