Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300008 | 0.95 | ITGB3 (0.41) | PPARDPPARAFFAR1ITGB3ITGA2B | |
| SCHEMBL7300477 | 0.83 | PPARA (0.49) | PPARDPPARAFFAR1ITGB3ITGA2B | |
| SCHEMBL7308662 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7298316 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2BMAPT | |
| SCHEMBL7301241 | 0.79 | MEN1 (0.37) | ITGB3ITGA2BLMNAKDM4EHPGD | |
| SCHEMBL7306389 | 0.79 | MEN1 (0.35) | ITGB3ITGA2BLMNAKDM4EHPGD | |
| SCHEMBL7298193 | 0.76 | ITGB3 (0.42) | PPARDPPARAFFAR1ITGB3ITGA2B | |
| SCHEMBL7307578 | 0.76 | ALDH1A1 (0.37) | ITGB3ITGA2BKMT2AALDH1A1MAPT | |
| SCHEMBL7304069 | 0.76 | FFAR1 (0.41) | FFAR1ITGB3ITGA2BLMNAKDM4E | |
| SCHEMBL7304075 | 0.76 | FFAR1 (0.41) | FFAR1ITGB3ITGA2BLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |