SCHEMBL7304241

SCHEMBL7304241

COc1cc2c(cc1C)CC(CCCCCC(=O)N1CCC[C@@H]1C(=O)N1CCSC1)CC2

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PREP P48147 13/20 0.53
HTR1A P08908 2/20 0.38
HTR7 P34969 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7304238 1.00 PREP (0.53) PREPHTR1AHTR7
SCHEMBL7301966 0.75 HTR1A (0.34) HTR1AHTR7
SCHEMBL7296561 0.74 PREP (0.75) PREP
SCHEMBL7433434 0.74 PREP (0.75) PREP
SCHEMBL7296556 0.73 PREP (0.53) PREP
SCHEMBL7293995 0.73 PREP (0.47) PREP
SCHEMBL7293303 0.72 PREP (0.46) PREPHTR1AHTR7
SCHEMBL7305043 0.72 PREP (0.73) PREP
SCHEMBL7305053 0.72 PREP (0.73) PREP
SCHEMBL7298452 0.72 LMNA (0.41) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed