Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316513 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2HTR2BITGB3ITGA2BCCR2 | |
| SCHEMBL7316726 | 0.91 | HTR7 (0.39) | SMN1; SMN2HTR7 | |
| SCHEMBL7303812 | 0.91 | MAOA (0.36) | SMN1; SMN2HTR2BITGB3ITGA2BMAOA | |
| SCHEMBL7313185 | 0.90 | ITGB3 (0.40) | HTR2BITGB3ITGA2BCCR2HTR7 | |
| SCHEMBL7310289 | 0.89 | GAA (0.34) | SMN1; SMN2HTR2BITGB3ITGA2BMAOA | |
| SCHEMBL7313418 | 0.87 | HTR2B (0.38) | SMN1; SMN2HTR2BMAOAHTR7 | |
| SCHEMBL7318017 | 0.87 | HTR7 (0.39) | SMN1; SMN2HTR7 | |
| SCHEMBL7309013 | 0.86 | HTR7 (0.37) | SMN1; SMN2HTR2BHTR7KCNH2 | |
| SCHEMBL7315008 | 0.86 | GAA (0.39) | SMN1; SMN2HTR2BHTR7KCNH2 | |
| SCHEMBL7317060 | 0.84 | MAPK1 (0.37) | SMN1; SMN2HTR2BITGB3ITGA2BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |