Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579526 | 0.84 | TCF4 (0.46) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL8579525 | 0.83 | LMNA (0.41) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL7307327 | 0.82 | HPGD (0.43) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL1716864 | 0.74 | ALDH1A1 (0.70) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL29875679 | 0.74 | ALDH1A1 (0.70) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL7304300 | 0.73 | HPGD (0.52) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL4104419 | 0.72 | ALDH1A1 (0.43) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL7387862 | 0.72 | HPGD (0.40) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL13656741 | 0.72 | GABRA1 (0.54) | HPGDALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL4116766 | 0.71 | ALDH1A1 (0.45) | HPGDALDH1A1TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |