Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 4/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301850 | 0.96 | ITGB3 (0.39) | ITGB3ITGA2BSMN1; SMN2SYKABCB1 | |
| SCHEMBL6476016 | 0.92 | ITGB3 (0.42) | ITGB3ITGA2BSMN1; SMN2ITGAV | |
| SCHEMBL7306172 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL7301488 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BSMN1; SMN2SYKPKM | |
| SCHEMBL6474456 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BSMN1; SMN2ITGAV | |
| SCHEMBL7306244 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BSMN1; SMN2SYKPKM | |
| SCHEMBL6483064 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL6480916 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2ITGAV | |
| SCHEMBL7422874 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL6474409 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2ITGAVPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |