Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483064 | 0.91 | ITGB3 (0.43) | ITGB3ITGA2BSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL7304338 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL7301850 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BSMN1; SMN2PKMMCHR1 | |
| SCHEMBL7301488 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL7306244 | 0.76 | ITGB3 (0.42) | ITGB3ITGA2BSMN1; SMN2PKMMCHR1 | |
| SCHEMBL6480916 | 0.70 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7422874 | 0.69 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL6480964 | 0.68 | ITGB3 (0.38) | ITGB3ITGA2BPOLB | |
| SCHEMBL6474409 | 0.67 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL7415330 | 0.65 | ITGB3 (0.51) | ITGB3ITGA2BPKMMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |