Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.47 |
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415330 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BYAP1KDM4EPKM | |
| SCHEMBL7422876 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BYAP1MAPTKDM4E | |
| SCHEMBL7425089 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EPKMMEN1 | |
| SCHEMBL7306244 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BPKMSMN1; SMN2 | |
| SCHEMBL7301488 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BPKMSMN1; SMN2 | |
| SCHEMBL7301850 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BPKMSMN1; SMN2 | |
| SCHEMBL7425099 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7304338 | 0.78 | ITGB3 (0.40) | ITGB3ITGA2BPKMSMN1; SMN2 | |
| SCHEMBL8687291 | 0.77 | ALDH1A1 (0.51) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL8147986 | 0.77 | YAP1 (0.62) | YAP1MAPTMAPK1NPSR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684823-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0684823-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |