Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306244 | 0.96 | ITGB3 (0.42) | ITGB3ITGA2BSYKBCHEACHE | |
| SCHEMBL6480916 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BBCHEACHESMN1; SMN2 | |
| SCHEMBL7304338 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BSYKSMN1; SMN2PKM | |
| SCHEMBL6474409 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BBCHEACHESMN1; SMN2 | |
| SCHEMBL7301850 | 0.85 | ITGB3 (0.39) | ITGB3ITGA2BSYKSMN1; SMN2PKM | |
| SCHEMBL7422874 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL6481898 | 0.80 | PKM (0.48) | ITGB3ITGA2BSMN1; SMN2LMNATP53 | |
| SCHEMBL7306172 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BSMN1; SMN2PKM | |
| SCHEMBL6474646 | 0.75 | SYK (0.40) | ITGB3ITGA2BSYKBCHEACHE | |
| SCHEMBL6475204 | 0.75 | PKM (0.49) | ITGB3ITGA2BSMN1; SMN2LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |