Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | EBP | Q15125 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240595 | 0.80 | L3MBTL1 (0.41) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL5752959 | 0.79 | EBP (0.51) | SLC22A1KCNH2CYP3A4TSHRL3MBTL1 | |
| SCHEMBL7310593 | 0.79 | EBP (0.51) | SLC22A1KCNH2CYP3A4TSHRL3MBTL1 | |
| SCHEMBL7315392 | 0.77 | BLM (0.41) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL8751246 | 0.75 | L3MBTL1 (0.61) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL5752266 | 0.75 | EBP (0.38) | CYP3A4TDP1EBPSIGMAR1CYP1A2 | |
| SCHEMBL10634290 | 0.74 | L3MBTL1 (0.44) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL5753392 | 0.74 | L3MBTL1 (0.44) | ADRB3CYP3A4L3MBTL1EBPSIGMAR1 | |
| SCHEMBL10631498 | 0.74 | L3MBTL1 (0.44) | ADRB3OPRK1KCNH2L3MBTL1EBP | |
| SCHEMBL10631515 | 0.72 | L3MBTL1 (0.42) | SLC22A1OPRK1PMP22KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |