Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240595 | 0.83 | L3MBTL1 (0.41) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL7304642 | 0.82 | EBP (0.54) | SLC22A1KCNH2CYP3A4TSHRCYP2D6 | |
| SCHEMBL7306091 | 0.82 | EBP (0.54) | SLC22A1KCNH2CYP3A4TSHRCYP2D6 | |
| SCHEMBL7304378 | 0.77 | BLM (0.37) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL7309344 | 0.75 | L3MBTL1 (0.37) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL7319271 | 0.75 | SLC22A2 (0.35) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL7314215 | 0.74 | SMN1; SMN2 (0.34) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL7302669 | 0.74 | HPGD (0.42) | TSHRTDP1EBPSIGMAR1L3MBTL1 | |
| SCHEMBL7309897 | 0.72 | TBXA2R (0.41) | TSHRCYP2D6SMN1; SMN2ALDH1A1TBXA2R | |
| SCHEMBL5751980 | 0.72 | EBP (0.51) | KCNH2CYP3A4TSHRCYP2D6EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |